Motor Skill Learning, Retention, and Control Deficits in Parkinson's Disease
نویسندگان
چکیده
منابع مشابه
Motor Skill Learning, Retention, and Control Deficits in Parkinson's Disease
Parkinson's disease, which affects the basal ganglia, is known to lead to various impairments of motor control. Since the basal ganglia have also been shown to be involved in learning processes, motor learning has frequently been investigated in this group of patients. However, results are still inconsistent, mainly due to skill levels and time scales of testing. To bridge across the time scale...
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BACKGROUND Previous studies have shown that primary motor cortex (M1) excitability is modulated by motor skill learning and that the M1 plays a crucial role in motor memory. However, the following questions remain: (1) At what stage do changes in M1 excitability occur? (2) Are learning-induced changes in leg M1 excitability associated with motor memory? Here, we did two experiments to answer th...
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The motor performance of patients with Parkinson's disease is degraded, but it is unclear whether their motor learning (adaptation learning and skill learning) ability is impaired. To assess the ability of these patients to learn motor tasks, we studied nine Parkinson's disease patients and eight age-matched normal (control) subjects who repetitively traced, as rapidly and accurately as possibl...
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One of the prominent disturbances in Parkinson's disease (PD) is bradykinesia. We studied performance of hand-to-mouth reach reaction time (RT) in right-handed PD patients and nine age and sex matched healthy control subjects. Participants practiced hand-to-mouth reach skill in response to a visual stimulus, 120 times a day for a period of one week. Using Kinemetrix 3D Motion Analysis system, t...
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The improvement of a perceptual or motor skill continues after training has ended. The central question is whether this improvement is just a function of time or whether sleep, a certain circadian phase, or their interaction (sleep occurring in a particular circadian phase) is favorable to the reprocessing of recent memory traces. In this issue of Neuron, provide behavioral evidence that most o...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0021669